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Posted: 10 17 2009 Post subject: chemotherapy hair hat loss scarf turban |
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| Pancreatic cancer is not as simple as this article makes it sound. I work in a lab at Purdue that works with a protein called Mist1, a DNA binding transcription factor. Mist1 is sort of the opposite of pdx1. Mist1 expression in the pancreas causes the pancreas to retain normal function, at least in mouse models. When its turned off and Kras is turned on in the pancreas, it typically ends poorly for the mice.The problem is that there is no one solution like this article leaves you to believe. Whether Kras is being overexpressed, pdx1 is being improperly expressed, or Mist1 turns off, or any other of dozens of problems are taking place, its always something different. Sorry to be the bubble burster, but this is only a hair on the head of the beast that is cancer. Just keep telling the government to fund science programs!! |
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